Focusrite Scarlett 16i16 (4th Gen)
A pro-tier USB-C interface with 16 outputs, loopback, phantom power, and ADAT-style expandability — one of the more capable line-return options in this batch. With many line returns it suits hybrid setups that lean on outboard and ADAT expansion. The catch is only two mic preamps, so anyone tracking several microphones at once should step up to the 18i16 or 18i20.
Specifications
| Spec | Value | Verification |
|---|---|---|
| connection | USB-C | high confidence |
| mic inputs | 2 | sourced |
| outputs | 16 | high confidence |
| phantom power | yes | high confidence |
| loopback | yes | unsourced detail |
4/5 specs sourced. Amber rows are unverified — we show them as reported, not confirmed.
Best for
- Hybrid setups with ADAT expansion needing many line returns
Who should skip this
- Tracking many mics at once (only 2 preamps; step up to 18i16/18i20)
Platform support
Compatibility
No platform-specific compatibility requirements — this works in any standard music production setup.
Upgrade path
Outgrow it and the PreSonus Quantum HD 2 is the natural next step up in audio interfaces. See it →
Sources (5 · 5 high-confidence)
Report an issue with this data →Every product carries its receipts. Field-level sources pin individual specs; flagged fields say so instead of guessing. Sources last retrieved 2026-06-12.
- primaryFocusrite - new Scarlett 16i16/18i16/18i20 ($399.99, 2 mic preamps, USB-C)manufacturer · high
- connectionUSB-C per Focusritemanufacturer · high
- mic_inputs2 mic preamps per Focusritemanufacturer · high
- outputsFocusrite - 16i16 has 16 inputs and 16 outputs (incl. ADAT/S/PDIF)manufacturer · high
- phantom_power48V on the two 4th-gen preamps per Focusritemanufacturer · high